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Summary of Lymphatic system

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Summary of Lymphatic system

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Body fluid
compartments
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Intracellular fluid

Extracellular fluid
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Interstitial fluid
Plasma
lymph
Movement of fluid
(factor : osmotic pressure,
hydrostatic pressure,
colloid osmotic pressure)
Plasma -> cell(RBC) ; RBC rupture
RBC -> plasma ; RBC collapse
Plasma -> interstitial fluid ; edema(d/t decrease colloid osmotic pressure)
Interstitial fluid -> plasma ; normal action
Interstitial fluid -> lymph ; normal action
Lymph -> interstitial fluid ; can not move
Lymphatic system
Lymph circulation : blood vessel -> interstitial fluid -> lymph capillaries -> lymph node
-> lymph duct right lymphatic duct ---> right subclavian vein subclavian vein
thoracic duct --------- > left subclavian vein

Lymphatic system Function
Role as pumps skeletal muscle pump
respiratory pump
Specific things compare to blood system ; 1-way opening/dead end lymphatic capillaries/lacteal
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Lymphatic organs and tissue
Primary lymphatic organs thymus : T cells mature
bone marrow ; produce WBC, lymphocyte, and T-cell ,B-cell.
B-cell mature
Secondary lymphatic organs lymph nodes : lymphocytes(B, T, natural killer cell)
spleen: destroy and stored blood cells
MALT: Peyer's patches(GI)
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Innate first line defense
second line defense antimicrobial substances
phagocytes neutrophils
macrophages wandering
fixed ; histiocyes/reticuloendothelial cells/
alveolar macrophages/microglia/tissue
the stage of phagocytosis by machrophages
natural killer cells
inflammation ; five symptoms/inflammatory response
fever ; hypothalamus

Adaptive Cell-mediated immunity :cytotoxic T cells, helper T cells, memory cells
/ effect intracellular pathogens
Antibody-mediated immunity: B cells transform into plasma cells, helper T cells, memory cells
/ plasma cells secret antibodies(IgA, IgG,IgM,IgD,IgA)
/ effect extracellular pathogens
/hypersensitivity reactions(Type I,II,III,IV)
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Immunity